Advantages of Toxoid in Diphtheria Prophylaxis
نویسندگان
چکیده
منابع مشابه
OPTIMIZATION OF DIPHTHERIA TOXOID PRECIPITATION BY USING SATURATED AMMONIUM SULPHATE IN ORDER TO IMPROVE DIPHTHERIA VACCINE
سابقه و هدف: کورینه باکتریوم دیفتریه باکتری هوازی و بیهوازی اختیاری است. مهمترین گونه از خانواده کورینه باکتریاها، عامل بیماری دیفتری است که به وسیله توکسین خود، بیماری دیفتری را ایجاد میکند. آمونیم سولفات نمکی معدنی است که از آن برای ترسیب و خالصسازی پروتئین ها استفاده میشود که با افزایش مقدار نمک حلالیت پروتئینی کم شده و پروتئین ها به واسطه قطعه های هیدروفوب خود، بههم پیوسته و رسو...
متن کاملPreparation and Evaluation of Diphtheria Toxoid-Containing Microspheres
Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT. In the first step, following the purification of semi-crude DT by the ion-exchan...
متن کاملThe Purification and Concentration of Diphtheria Toxoid
By precipitation with acetone at 4 degrees C. a refined diphtheria toxoid was obtained as a dry powder, readily soluble in aqueous solutions. The powder itself appears to be stable. When dissolved in half the original volume of physiological salt solution, the toxoid remained stable, in the cold room, for a period of 7 months. Only toxoids should be used which have been completely detoxified by...
متن کاملPreparation and Evaluation of Diphtheria Toxoid-Containing Microspheres
Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT. In the first step, following the purification of semi-crude DT by the ion-exchan...
متن کاملSafety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis and Influenza Vaccinations in Pregnancy.
OBJECTIVE To evaluate the safety of coadministering tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) and influenza vaccines during pregnancy by comparing adverse events after concomitant and sequential vaccination. METHODS We conducted a retrospective cohort study of pregnant women aged 14-49 years in the Vaccine Safety Datalink from January 1, 2007, to November 15, 2...
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ژورنال
عنوان ژورنال: American Journal of Public Health and the Nations Health
سال: 1932
ISSN: 0002-9572
DOI: 10.2105/ajph.22.1.17